Holbrook is between Melbourne and Sydney on the Hume Highway, approx 60km north of Albury. Visitors to the town are greeted by the unlikely sight of a submarine, HMAS Otway, next to the submarine museum and visitors information centre. The Submarine Precinct is a well known stop over on the Hume Highway. For those who stay longer, The Woolpack Inn Museum is a two story heritage listed historic building located in the main street of Holbrook, and the National Museum of Australian Pottery is the only Museum dedicated to 19th and early 20th century Australian pottery and the Holbrook Miniature Railway will appeal to many.
Holbrook is the largest town in Greater Hume Shire.